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Tue, Sep 1, 2026 · 5:00 – 6:00 AM Bangkok
Understanding Your Care Journey: From Testing to Treatment
Brian L. Miller II
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Fulcrum plummets over 50% after scrapping lead sickle-cell drug on FDA concerns

Source
Reuters

June 2 (Reuters) - Shares of Fulcrum Therapeutics (FULC.O), opens new tab plunged 52% on Tuesday after the company said it would abandon development ​of its experimental sickle-cell disease drug following cancer-risk concerns raised by the ‌U.S. FDA, and explore strategic options including a potential sale or merger.

The oral drug, pociredir, was being tested to treat sickle-cell disease, an inherited blood disorder that can trigger pain, ​anemia and organ damage and reduce life expectancy.