Clinical Trials and Research

Orbital compression syndrome (OCS), also referred to in the sickle cell disease (SCD) literature as orbital infarction syndrome, is an uncommon but potentially…

AbstractSickle cell disease (SCD) is a monogenic hemoglobinopathy in which hemoglobin S (HbS) polymerizes on deoxygenation, leading to sickling of red blood cells (…

AbstractBackground: Sickle cell disease (SCD) is a major cause of morbidity and mortality among children in sub-Saharan African. Hydroxyurea (HU) remains the…

Background: Sickle Cell Disease (SCD) causes acute and chronic complications. Hydroxyurea (HU) reduces vaso-occlusive crises (VOCs), and improves patients’ outcomes…

Zydus Lifesciences is advancing its clinical pipeline with permission to start Phase III clinical trials of Desidustat, an oral therapeutic candidate for Sickle…

AbstractSickle cell disease (SCD) is a globally distributed hereditary red cell disorder with still high mortality. Growing evidence indicates that sickle cell…