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Sickle cell advocates are urging government and policymakers to introduce subsidies and improve access to affordable medication for Nigerians living with sickle cell anaemia. While highlighting the financial burden of treatment, they also stressed the importance of genotype awareness, encouraging citizens to make informed choices in relationships to reduce the risk of passing the condition on. Our correspondent, Idong Joseph, reports on the growing call for systemic support, better healthcare policies, and increased public awareness to address the needs of those affected.