Scientific Articles

A high dose of pociredir, Fulcrum Therapeuticsexternal link, opens in a new tab’ oral drug candidate for sickle cell diseaseexternal link, opens in a new tab (SCD…

AbstractNewborn screening helps identify sickle cell disorder (SCD) early and to promptly initiate effective measures. It is estimated that India accounts for…

A small clinical trial testing Agios Pharmaceuticalsexternal link, opens in a new tab’ oral therapy candidate tebapivat against a placebo for easing symptoms in…

AbstractBackgroundSickle cell disease (SCD) is a genetic blood disorder most prevalent in Eastern and Western Africa. With the high prevalence of SCD in northern…

AbstractSickle cell disease (SCD) is a hereditary disorder characterized by HBB variants, leading to chronic hemolytic anemia and vaso-occlusion. Hepatobiliary…

ABSTRACTSickle Cell Disease (SCD) is a group of disorders associated with mutations in the β-globin (HBB) gene and defined by the presence of haemoglobin S (HbS).…

The Food and Drug Administration (FDA) has granted breakthrough device designation to the Gazelle Hb Variant test, a point-of-care blood test developed by …

Abstractβ-thalassemia and sickle cell disease are two inherited hematological diseases due to defective hemoglobin synthesis or to the production of hemoglobin with…

AbstractSickle cell disease (SCD) is the most common inherited clinically relevant blood disorder. Although a deceptively simple monogenetic disorder, the…

Testing blood levels of certain clotting proteins may help clinicians identify serious complications of sickle cell diseaseexternal link, opens in a new tab (SCD)…