News

Main PointsHigh MPV and neutrophils with low PNR may act as accessible hematological signatures for VOC and ischemic stroke in pediatric SCD.Platelet indices could…

AbstractIntroduction: Sickle cell disease (SCD) is associated with systemic complications, including sensorineural hearing loss (SNHL) from microvascular occlusion…

Twice-daily (BID) deferiprone (DFP) appeared well-tolerated in a real-world study that included patients with thalassemia, sickle cell disease (SCD), or other…

A 19-year-old’s death was followed by another blow for his family when India Post rejected his Rs 7 lakh Rural Postal Life Insurance (RPLI) claim, alleging that his…

I wrote here a couple of years ago about the problems being experienced by Bluebird Bio, pioneers in commercializing human gene therapies. The summary is that…

HIGHLIGHTSSCD-CARRE is the first randomized controlled trial to compare chronic red blood cell exchange transfusion to standard of care in high-risk adults with…

AbstractSickle cell anemia (SCA) is characterized by chronic hemolysis, vaso-occlusion, sustained inflammation, immune dysfunction, and increased susceptibility to…

The U.S. Food and Drug Administration (FDA) has granted priority review — a decision that could speed a drug’s approval — to an application for the oral therapy…

Background Sickle cell disease (SCD) is a global public health concern with high morbidity and mortality among children, particularly in low-and-middle-income…

AbstractChildren with sickle cell anemia (SCA) have poor growth and pubertal development. REACH (Realizing Effectiveness Across Continents with Hydroxyurea) is a…