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ObjectivesTo determine whether adults with sickle cell disease (SCD) without glaucoma exhibit subclinical structural optic neuropathy (SON) on optical coherence…

Casgevy’s approval changed the sickle cell disease landscape. Developed by Vertex Pharmaceuticals and CRISPR Therapeutics, the therapy showed that the…

A reduced-intensity bone marrow transplant regimen developed by Johns Hopkins physicians provides durable engraftment with low rejection rates and also may preserve…

What are the main findings?Endothelial dysfunction is a hallmark of sickle cell disease (SCD), which is associated with both acute and chronic crises in patients.…

Sickle cell disease (SCD) hospitalization patterns vary across New York State, with New York City showing the largest share of hospitalizations and Long Island…

Sickle cell disease is the scourge of a person’s red blood cells. The inherited blood disorder, which disproportionately affects people in sub-Saharan Africa and…

Data from a large New York State analysis found that sickle cell disease hospitalizations are becoming more severe over time, with significant regional disparities…

Key PointsThis is the first SCD project to implement a privacy-preserving technique for linking individuals across multiple registries.Linkage of multiple…

Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. Approximately 10 percent of people with SCD in the US live in New York…

Article summarySickle Cell Disease (SCD) poses a significant health challenge in low- and middle-income countries, particularly in sub-Saharan Africa, where access…