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Sickle cell disease (SCD) is a chronic, inherited condition rising across the globe. Prior studies revealed a direct link between the gut microbiome and disease…

AbstractSickle cell disease (SCD) is a monogenic disorder marked by hemoglobin S polymerization, resulting in chronic hemolysis, vaso-occlusion, systemic…

SAN ANTONIO - The official cause of death for a Bexar County Jail inmate who died in May has finally been released.According to the Bexar County Medical Examiner's…

A woman who suffered a medical emergency in her cell at the Bexar County jail earlier this year died of complications from sickle cell disease, the Bexar…

The multicenter trial is evaluating a CRISPR-Cas9 approach designed to directly modify the beta‑globin gene in sickle cell disease.FDA-approved gene therapies have…

Health experts have urged Ugandans to undergo screening for sickle cell disease, warning that many people are living with the inherited condition undiagnosed,…

AbstractBackground: Sickle cell disease (SCD) is the most common inherited blood disorder globally, affecting approximately 300,000 newborns annually. Cardiac…

The Clinical, Medical and Regulatory (CMR) department at Novo Nordisk is one of the most diverse and collaborative groups within the organization. From healthcare…

AbstractBackground: Sickle cell disease (SCD) is a major inherited haemoglobin disorder and a leading cause of childhood morbidity and mortality in sub-Saharan…

AbstractAllogeneic hematopoietic cell transplantation (HCT) and autologous hematopoietic stem cell–based gene therapies are potentially curative for sickle cell…