Clinical Trials and Research

AbstractSickle Cell Disease (SCD) remains a public health challenge in India, particularly among tribal populations. Gaps persist in early detection, awareness, and…

Editas Medicine has reported positive outcomes for a gene editing treatment to treat severe sickle cell disease, a hereditary blood disorder with limited treatment…

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B)…

Sickle cell disease is characterized by chronic hemolytic anemia and recurrent severe vaso-occlusive crises. Ristoglogene autogetemcel (risto-cel) includes…

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative…

Blood is often pictured as a smooth, continuous stream, but in reality it behaves more like rush-hour traffic in a dense city with crowded lanes, sudden merges and…

Recent studies have reached opposing conclusions about whether clonal hematopoiesis (CH) is increased or decreased in patients with sickle cell disease (SCD). Given…

Through a project aimed at building empathy and understanding among clinicians about sickle cell disease (SCD)-related pain episodes, a team of nurses in Chicago…

Omolola Kafayat AwolopeDepartment of Medical Laboratory Science, Afe Babalola University, Ado Ekiti, Ekiti State, Nigeria.David Olufemi AdeboDepartment of Clinical…

ABSTRACTSickle cell disease (SCD) is the most common inherited hemoglobinopathy worldwide. Improving the quality of life of people with SCD requires prenatal and…