Clinical Trials and Research

Editas Medicine has reported positive outcomes for a gene editing treatment to treat severe sickle cell disease, a hereditary blood disorder with limited treatment…

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B)…

Sickle cell disease is characterized by chronic hemolytic anemia and recurrent severe vaso-occlusive crises. Ristoglogene autogetemcel (risto-cel) includes…

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative…

Blood is often pictured as a smooth, continuous stream, but in reality it behaves more like rush-hour traffic in a dense city with crowded lanes, sudden merges and…

Recent studies have reached opposing conclusions about whether clonal hematopoiesis (CH) is increased or decreased in patients with sickle cell disease (SCD). Given…