Clinical Trials and Research

We are a specialist centre for the diagnosis and management of adults with inherited haemoglobin disorders including sickle cell disease, thalassaemia.Who we seeWe…

IntroductionSickle cell disease (SCD) is the most common inherited blood disorder in the USA and globally, with a gradual increase in prevalence (1). SCD continues…

AbstractBackgroundSickle cell disease (SCD) is a genetic hemoglobinopathy that disproportionately affects individuals of African descent and is associated with…

AbstractHLA-identical sibling donor hematopoietic cell transplant (HCT) is an established curative therapy for sickle cell disease (SCD). Although myeloablative HCT…

AbstractSickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and…

AbstractBackgroundExagamglogene autotemcel (exa-cel) is a cell therapy in which autologous CD34+ hematopoietic cells are engineered through ex vivo clustered…

AbstractIntroduction: Sickle cell disease (SCD) is a group of inherited blood diseases in which the affected person inherits two abnormal haemoglobin genes from…

Courtney is an Ivy League–educated investment banker on Wall Street. She loves to travel, enjoys Broadway musicals and lives in New York City with her two best…

Stem cell transplant from a partially matched donor is more cost-effective than gene therapy to treat sickle cell disease (SCD), according to a study.In order for…

A 10-year study in sub-Saharan Africa revealed that a higher dose of the oral medication Hydroxyurea improved survival and growth outcomes in children with sickle…